Afraid of spiders? You will be…

Holy crap, Lolth is nasty in 4E! 😯

Dungeons & Dragons Roleplaying Game Official Home Page – Article (Lolth)

Just as a sample, I give you:

Dominating Rebuke (charm) * At-Will

Trigger: An enemy hits Lolth.

Effect (Immediate Reaction): The triggering enemy is dominated until the end of the enemy’s next turn.

(Any group that missed or ignores the "one immediate action/round" rule is going to die of apoplexy…) 😉