Holy crap, Lolth is nasty in 4E! 😯
Just as a sample, I give you:
Dominating Rebuke (charm) * At-Will
Trigger: An enemy hits Lolth.
Effect (Immediate Reaction): The triggering enemy is dominated until the end of the enemy’s next turn.
(Any group that missed or ignores the "one immediate action/round" rule is going to die of apoplexy…) 😉